In the past, I put Ubuntu and Debian. If I remember correctly, they worked fine. At least, I can not remember the inconvenience associated with the lack of scrolling. Unfortunately, the version with GUI these OSs are quite heavy for my system. And they did not take root.
Of course, a bunch of guest Windows of different versions works normally and stably, as one would expect for a hypervisor embedded in Windows host.
I didn’t even try to check the scroll with other mouse, because I understand that the VM works with emulated devices.
Now with a direct question and to clear my conscience, I checked another wireless mouse and a regular USB Mouse with a cord. It did not help – it’s not the mice issue.